Study Shows Image-Guided SRT Has 99.3% Cure Rate

By News Release


According to a study, Image-Guided Superficial Radiotherapy (Image-Guided SRT) published in Oncology and Therapy, the most advanced non-surgical technology for the treatment of common skin cancers, is 99.3% effective in treating basal cell carcinoma and squamous cell carcinoma. SkinCure Oncology announced the results of the study, which is one of the largest multi-institutional studies of superficial radiotherapy for the treatment of these cancers.

Researchers evaluated the medical records of 1,632 patients with a combined 2,917 stage 0-2 lesions treated with Image-Guided SRT, a technology that eradicates skin cancer using low levels of x-rays combined with the modern radiotherapy protocols utilized by SkinCure Oncology Practice Partners. Of the lesions that were treated with Image-Guided SRT, 2,897, or 99.3%, did not have evidence of disease at the patients’ last follow-up visit. The mean duration of follow-up was 69.8 weeks. Fifty-seven percent of subjects were male and 43% were female, all with a mean age of 73.2 years.

Prior to the availability of Image-Guided SRT, individuals with these cancers had limited treatment options, including cryosurgery, earlier versions of superficial radiotherapy without imaging capabilities, and Mohs surgery. The latter invasive surgical procedure, introduced more than 80 years ago, requires anesthesia, use of a scalpel, and post-surgical suture/stitch removal, which can result in scarring around the treated area and require subsequent reconstructive or cosmetic surgery. Alternatively, Image-Guided SRT delivers a precise and calibrated dose of x-rays that destroy malignant cancer cells without surgery while preserving healthy tissue surrounding the treated areas

“The results of this study demonstrate that Image-Guided SRT should be considered as a first-line treatment option for early-stage basal cell and squamous cell carcinoma,” said study co-author Christopher R. Shea, MD, dermatologist and professor of medicine at the University of Chicago.

Dr. Shea’s co-authors were New York radiation oncologist Lio Yu, MD, and Chad K. Oh, MD, currently chief medical officer at AEON Biopharma in California.

“This significant study affirms what we have been seeing in clinical practices across the country that offer Image-Guided SRT as an option to their patients,” said SkinCure Oncology Co-Founder and CEO Kerwin J. Brandt. “This next-generation skin cancer treatment, when coupled with our comprehensive program, is a gamechanger in dermatology, and we are honored to facilitate its use for the benefit of those millions of people who are diagnosed with skin cancer every year.”