Applied Radiation Oncology

Artificial Intelligence · Prostate Cancer

Avenda Health Introduces Surgery Mode for Enhanced Prostate Cancer Mapping

October 21, 2026 · News Release

Source: Cision PR Newswire

Avenda Health has announced the launch of Surgery Mode, a new suite of features for its Unfold AI platform, designed to improve intraoperative guidance during prostate cancer surgeries. This enhancement aims to provide surgeons with a detailed 3D cancer mapping experience in real-time, allowing for a more precise understanding of cancer anatomy during procedures.

Surgery Mode facilitates the integration of Unfold AI directly into the operating room, moving beyond traditional pre-surgical consults. Key features include an updated Capsule Risk Score map that automatically adjusts its orientation to align with the surgical camera view, delivering instant risk feedback by quadrant. This functionality supports critical decision-making regarding nerve-sparing surgical approaches.

The Unfold AI platform specializes in clinical decision-making for various aspects of prostate cancer care, including active surveillance, focal therapy, radiation oncology, and surgical options. The development of Surgery Mode builds on prior peer-reviewed research indicating that the platform could significantly reduce positive surgical margins and cancer recurrence rates.

Notably, Unfold AI is recognized for its superior ability to determine cancer spread compared to MRI, thus aiding surgeons in their decision-making processes. Surgery Mode provides several operational improvements, such as:

  • Aligned Capsule Risk Score Mapping: The updated risk score now automatically mirrors the surgical camera view, offering immediate, color-coded feedback to assist in nerve-sparing decisions.
  • Redesigned Patient List and Case Filters: Enhancements allow for improved organization of patient cases, enabling users to filter and search effectively during procedures.
  • Improved Administrative Control: New tools are available to verify insurance approvals and confirm that necessary administrative steps have been completed before generating 3D maps.
  • Streamlined Case Management: Care teams can now add notes and update physician assignments directly from patient lists, enhancing workflow efficiency.

According to Shyam Natarajan, Ph.D., co-founder and CEO of Avenda Health, these developments aim to deliver greater clinical clarity throughout a patient’s cancer journey, providing essential visual guidance for decisions ranging from counseling newly diagnosed patients to performing complex surgical procedures.

Avenda Health's Unfold AI predicts the extent of cancer spread with 92% accuracy, a significant improvement over the 52% accuracy achieved with MRI alone. Research indicates that the platform enhances tumor identification sensitivity from 37% to 97%, further underscoring its utility in surgical settings.

With the introduction of Surgery Mode, Avenda Health expands its capabilities in personalized prostate cancer care, integrating sophisticated 3D mapping technology into real-time surgical practices, ultimately enhancing patient care and outcomes.

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